Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2255542 | 0.81 | TDP1 (0.48) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL10697600 | 0.77 | TDP1 (0.44) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL4721887 | 0.77 | ALDH1A1 (0.36) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL3483559 | 0.77 | TDP1 (0.40) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL10583869 | 0.76 | TDP1 (0.43) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL2257955 | 0.74 | TDP1 (0.41) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL943520 | 0.74 | MAPT (0.51) | ALDH1A1TSHRHSD17B10LMNAATM | |
| SCHEMBL809522 | 0.72 | TDP1 (0.40) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL14292863 | 0.72 | ALDH1A1 (0.40) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL941713 | 0.72 | ALDH1A1 (0.40) | TDP1ALDH1A1TSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447368-A | Process for the preparation of aminoarylsulphonic acids in sulfolene solvent | SIEMENS-ALLIS, INC. (US) | 1984-05-08 | — | — | US | disclosed |
| US-4435336-A | FROM ARYLAMINE AND SULFONIC ACID, OR CORRESPONDING ARYLAMMONIUM HY | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-06 | — | — | US | disclosed |