Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10571685 | 0.86 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL11071393 | 0.86 | SCN1A (0.49) | KCNH2SCN1ASCN5ASCN9ASLC18A3 | |
| SCHEMBL11071869 | 0.79 | SCN1A (0.55) | KCNH2SCN1ASCN5ASCN9ASLC18A3 | |
| SCHEMBL11064138 | 0.77 | KCNH2 (0.64) | KCNH2SCN1ASCN5ASCN9ASLC18A3 | |
| SCHEMBL11073822 | 0.77 | KCNH2 (0.54) | KCNH2SCN1ASCN5ASCN9APRMT5 | |
| SCHEMBL10568098 | 0.76 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL11066783 | 0.76 | SLC18A3 (0.38) | KCNH2SCN1ASCN5ASCN9ASLC18A3 | |
| SCHEMBL11069036 | 0.75 | SCN1A (0.52) | KCNH2SCN1ASCN5ASCN9ASLC18A3 | |
| SCHEMBL11066594 | 0.72 | MAOB (0.57) | — | |
| SCHEMBL11061316 | 0.72 | SCN5A (0.69) | KCNH2SCN1ASCN5ASCN9ASLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |