Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071003 | 0.92 | MAPK14 (0.42) | MAPK14SRD5A1SMN1; SMN2AOC3TSHR | |
| SCHEMBL11068179 | 0.90 | L3MBTL1 (0.45) | SRD5A1L3MBTL1SMN1; SMN2AOC3LMNA | |
| SCHEMBL11075121 | 0.90 | AKR1B1 (0.39) | MAPK14SRD5A1DHODHAKR1B1 | |
| SCHEMBL11065609 | 0.88 | HRH1 (0.39) | SRD5A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11073141 | 0.86 | AKR1B1 (0.42) | L3MBTL1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL11068485 | 0.82 | L3MBTL1 (0.42) | MAPK14SRD5A1L3MBTL1SMN1; SMN2AOC3 | |
| SCHEMBL11066911 | 0.80 | KDM1A (0.41) | SRD5A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11070255 | 0.80 | AKR1B1 (0.40) | SRD5A1L3MBTL1LMNAMAPTMEN1 | |
| SCHEMBL11182632 | 0.80 | SMN1; SMN2 (0.35) | L3MBTL1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL11187765 | 0.79 | L3MBTL1 (0.35) | L3MBTL1SMN1; SMN2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444981-A | ANTIINFLAMMATORY, ANALGESICS | BEECHAM GROUP LIMITED (GB) | 1984-04-24 | — | — | US | disclosed |
| EP-0024807-B1 | BENZOCYCLOHEPTAPYRROLEALKANOIC ACIDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-11-02 | — | — | EP | disclosed |