Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071289 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL11063693 | 0.81 | HCAR3 (0.41) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL23143772 | 0.78 | MAPT (0.51) | KDM4EALDH1A1MAPTHSD17B10ATM | |
| SCHEMBL29811877 | 0.78 | MAPT (0.51) | KDM4EALDH1A1MAPTHSD17B10ATM | |
| SCHEMBL31750534 | 0.76 | CA1 (0.56) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL30871180 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL11066299 | 0.73 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL30871556 | 0.73 | NOTUM (0.46) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL29208134 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTHPGDATM | |
| SCHEMBL12421799 | 0.70 | POLB (0.58) | KDM4EALDH1A1MAPTHPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |