Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065600 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL11063693 | 0.84 | HCAR3 (0.41) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL11068685 | 0.83 | HSD17B3 (0.41) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL22097615 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL11066299 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL1543144 | 0.76 | GAA (0.71) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL11068912 | 0.75 | METAP2 (0.45) | ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9402430 | 0.73 | ALDH1A1 (0.65) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL2014323 | 0.73 | LNPEP (0.56) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL22415248 | 0.72 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |