Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382467 | 0.80 | POLB (0.43) | POLBCYP2C19CYP3A4CYP2C9HMGCR | |
| SCHEMBL32679459 | 0.80 | LMNA (0.59) | POLBCYP2C19CYP3A4CYP2C9HMGCR | |
| SCHEMBL4462235 | 0.75 | POLB (0.50) | POLBCYP2C19CYP3A4CYP2C9HMGCR | |
| SCHEMBL3904945 | 0.75 | POLB (0.50) | POLBCYP2C19CYP3A4CYP2C9HMGCR | |
| SCHEMBL9050380 | 0.74 | POLB (0.46) | POLBCYP2C19CYP3A4CYP2C9HMGCR | |
| SCHEMBL21511095 | 0.74 | HMGCR (0.42) | POLBCYP2C19CYP3A4CYP2C9HMGCR | |
| SCHEMBL8373901 | 0.73 | LMNA (0.62) | CYP2C19LMNA | |
| SCHEMBL3822346 | 0.73 | POLB (0.48) | POLBCYP2C19CYP3A4CYP2C9HMGCR | |
| SCHEMBL4402436 | 0.73 | TSHR (0.40) | POLBCYP2C19CYP3A4CYP2C9HMGCR | |
| SCHEMBL22304385 | 0.72 | CYP3A4 (0.38) | POLBCYP2C19CYP3A4CYP2C9HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4471118-A | Preparation of aldehydes by heating an α-hydroxyphosphonic acid ester | BAYER AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |