SCHEMBL5382467

SCHEMBL5382467

CCOP(=O)(OCC)C(O)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
GAA P10253 3/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
CYP2C19 P33261 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
HMGCR P04035 2/20 0.39
TSHR P16473 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PPARD Q03181 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11065753 0.80 POLB (0.44) POLBGAALMNACYP2C19CYP3A4
SCHEMBL32679459 0.78 LMNA (0.59) POLBALDH1A1MAPTGAAKDM4E
SCHEMBL27687653 0.75 POLB (0.47) POLBGAACYP2C19CYP3A4CYP2C9
SCHEMBL3904945 0.74 POLB (0.50) POLBGAACYP2C19CYP3A4CYP2C9
SCHEMBL4462235 0.74 POLB (0.50) POLBGAACYP2C19CYP3A4CYP2C9
SCHEMBL24195717 0.72 TSHR (0.37) POLBALDH1A1MAPTRAB9AGAA
SCHEMBL21016805 0.72 TSHR (0.37) POLBALDH1A1MAPTRAB9AGAA
SCHEMBL27666361 0.72 POLB (0.39) POLBALDH1A1MAPTRAB9AGAA
SCHEMBL3822346 0.72 POLB (0.48) POLBGAACYP2C19CYP3A4CYP2C9
SCHEMBL11045698 0.71 POLB (0.44) POLBALDH1A1GAACYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109223579-B Dental restoration material and preparation method thereof 张庆鹏 2021-04-13 CN claimed
US-6306203-B1 FOR USE IN INK JET PRINTING, INCLUDING PIEZOELECTRIC INK JET PRINTING AND ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-10-23 US claimed
CN-109223579-B Dental restoration material and preparation method thereof 张庆鹏 2021-04-13 CN disclosed
US-7285610-B2 Synthesis method for polymers by controlled radical polymerisation with xanthates RHODIA CHIMIE (FR) 2007-10-23 US disclosed
US-7285610-B2 Synthesis method for polymers by controlled radical polymerisation with xanthates RHODIA CHIMIE (FR) 2007-10-23 US disclosed
US-7285610-B2 Synthesis method for polymers by controlled radical polymerisation with xanthates RHODIA CHIMIE (FR) 2007-10-23 US disclosed
US-20050054794-A1 Synthesis method for polymers by controlled radical polymerisation with xanthates RHODIA CHIMIE (FR) 2005-03-10 US disclosed
US-6809164-B2 FORMING LOW POLYDISPERSITY MATERIALS RHODIA CHIMIE (FR) 2004-10-26 US disclosed
EP-1242467-B1 SYNTHESIS METHOD FOR POLYMERS BY CONTROLLED RADICAL POLYMERISATION WITH XANTHATES RHODIA CHIMIE SA (FR) 2004-08-11 EP disclosed
US-6509393-B2 Phase change inks XEROX CORPORATION 2003-01-21 US disclosed
EP-1242467-A1 SYNTHESIS METHOD FOR POLYMERS BY CONTROLLED RADICAL POLYMERISATION WITH XANTHATES RHODIA CHIMIE (FR) 2002-09-25 EP disclosed
US-6395077-B1 INKS WITH BENZOYLBENZOIC ACID AND COLORS XEROX CORPORATION 2002-05-28 US disclosed
US-6306203-B1 FOR USE IN INK JET PRINTING, INCLUDING PIEZOELECTRIC INK JET PRINTING AND ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-10-23 US disclosed
WO-2001042312-A1 SYNTHESIS METHOD FOR POLYMERS BY CONTROLLED RADICAL POLYMERISATION WITH XANTHATES RHODIA CHIMIE (FR) 2001-06-14 WO disclosed