Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.71 |
| ▸ | MAOA | P21397 | 12/20 | 0.64 |
| ▸ | MAOB | P27338 | 12/20 | 0.64 |
| ▸ | HTR6 | P50406 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070978 | 0.85 | DRD2 (0.71) | DRD2MAOAMAOBHTR6DRD4 | |
| SCHEMBL11071264 | 0.85 | DRD2 (0.82) | DRD2MAOAMAOBHTR6DRD4 | |
| SCHEMBL11073358 | 0.85 | DRD2 (0.70) | DRD2MAOAMAOBHTR6 | |
| SCHEMBL11066962 | 0.85 | DRD2 (0.68) | DRD2MAOAMAOBHTR6DRD4 | |
| SCHEMBL11063092 | 0.84 | DRD2 (0.53) | DRD2MAOAMAOBHTR6 | |
| SCHEMBL10428728 | 0.83 | DRD2 (0.94) | DRD2MAOAHTR6DRD4DRD3 | |
| SCHEMBL11074474 | 0.83 | MAOA (0.68) | DRD2MAOAMAOBDRD4DRD3 | |
| SCHEMBL11066640 | 0.83 | MAOA (0.71) | DRD2MAOAMAOBHTR6 | |
| Hydrochloric Acid SCHEMBL11070913 | 0.82 | DRD2 (0.52) | DRD2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11068783 | 0.82 | MAOA (0.70) | DRD2MAOAMAOBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |