SCHEMBL11066052

SCHEMBL11066052

CCCC1CC(C(=O)OC)C(=O)CC1=O

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 1/20 0.33
TLR4 O00206 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
DNTT P04053 1/20 0.33
FKBP1A P62942 1/20 0.32
ALOX12 P18054 1/20 0.31
SLC6A3 Q01959 1/20 0.31
CHRNB2 P17787 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
CHRNB3 Q05901 1/20 0.30
CHRNA6 Q15825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11069729 0.87 BRD4 (0.34) SMN1; SMN2KDM4EALDH1A1MAPTCHRNB2
SCHEMBL11065757 0.79 TSHR (0.33) TSHRSMN1; SMN2HTTTLR4DNTT
SCHEMBL11059934 0.76 TSHR (0.33) TSHRSMN1; SMN2HTTALDH1A1DNTT
SCHEMBL11062133 0.74 ALDH1A1 (0.34) TLR4ALDH1A1CHRNB2CHRNA3CHRNA4
SCHEMBL11770967 0.73 FKBP1A (0.36) TSHRSMN1; SMN2HTTTLR4KDM4E
SCHEMBL2286701 0.73 TLR4 (0.56) TSHRSMN1; SMN2HTTTLR4KDM4E
SCHEMBL11069395 0.73 SLC6A3 (0.32) TSHRSMN1; SMN2HTTDNTTSLC6A3
SCHEMBL11061482 0.72 TSHR (0.33) TSHRSMN1; SMN2HTTALDH1A1DNTT
SCHEMBL11058336 0.70 DNTT (0.38) TSHRSMN1; SMN2HTTALDH1A1DNTT
SCHEMBL11055929 0.69 BRD4 (0.33) TLR4ALDH1A1CHRNB2CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4432378-A ORGANOLEPTIC; TOBACCO; FOODS; DETERGENTS; COSMETICS FRITZSCHE, DODGE & OLCOTT, INC. (US) 1984-02-21 US disclosed
US-4326996-A FOR PERFUMES FRITZSCHE DODGE & OLCOTT INC. (US) 1982-04-27 US disclosed
US-4281204-A ALKYLATION, DECARBOXYLATION TO CYCLIZE FRITZSCHE DODGE & OLCOTT INC. (US) 1981-07-28 US disclosed