Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947657 | 0.87 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP3A4TSHRHTT | |
| SCHEMBL9220119 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CYP3A4TSHRHTT | |
| SCHEMBL17986638 | 0.81 | RAPGEF4 (0.53) | ALDH1A1HSD17B10TSHRTDP1RAPGEF4 | |
| SCHEMBL29961547 | 0.80 | RAPGEF4 (0.61) | ALDH1A1RAPGEF4KMT2AMAPTMEN1 | |
| SCHEMBL1687027 | 0.80 | RAPGEF4 (0.61) | ALDH1A1RAPGEF4KMT2AMAPTMEN1 | |
| SCHEMBL29961149 | 0.80 | RAPGEF4 (0.61) | ALDH1A1RAPGEF4KMT2AMAPTMEN1 | |
| SCHEMBL9225044 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HSD17B10CYP3A4TSHRHTT | |
| SCHEMBL11061197 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HSD17B10CYP3A4TSHRHTT | |
| SCHEMBL9224929 | 0.79 | HTT (0.63) | ALDH1A1HSD17B10CYP3A4TSHRHTT | |
| SCHEMBL28877113 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HSD17B10CYP3A4TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448994-A | Reduction of C-nitrosoarylamines | UOP INC. (US) | 1984-05-15 | — | — | US | disclosed |