SCHEMBL29947657

SCHEMBL29947657

O=Nc1ccc(Nc2cccc(Nc3ccc(N=O)cc3)c2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.76
HSD17B10 Q99714 6/20 0.76
TSHR P16473 3/20 0.76
TDP1 Q9NUW8 3/20 0.76
CYP3A4 P08684 3/20 0.76
HTT P42858 1/20 0.76
KMT2A Q03164 5/20 0.56
MAPT P10636 5/20 0.56
MEN1 O00255 3/20 0.56
AR P10275 1/20 0.56
MAPK1 P28482 3/20 0.44
ALOX12 P18054 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALOX15 P16050 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
PTGS2 P35354 1/20 0.44
HTR2B P41595 1/20 0.44
GAA P10253 3/20 0.42
LMNA P02545 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28877113 0.87 ALDH1A1 (0.63) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL9224929 0.87 HTT (0.63) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL11066176 0.87 ALDH1A1 (0.63) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL9225044 0.87 ALDH1A1 (0.63) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL11061197 0.87 ALDH1A1 (0.63) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL655572 0.86 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRTDP1CYP3A4
Hydrochloric Acid SCHEMBL716679 0.84 ALDH1A1 (0.95) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL10866233 0.84 ALDH1A1 (0.95) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL9224466 0.82 KIF11 (0.60) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL8966246 0.81 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260041-A Novel anti-aging agent and preparation method thereof 王兴路 2022-11-01 CN disclosed