Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529427 | 0.77 | ALDH1A1 (0.41) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14414582 | 0.77 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL2980649 | 0.75 | CYP1A2 (0.49) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15165636 | 0.74 | MAPT (0.57) | MAPTCYP1A2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL3291066 | 0.73 | CYP11B1 (0.43) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15832003 | 0.73 | ADORA1 (0.51) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL25510512 | 0.72 | RPS6KB2 (0.41) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6440667 | 0.72 | ADORA2A (0.59) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6251736 | 0.71 | MAPT (0.66) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3089787 | 0.71 | ADORA2A (0.53) | MAPTKDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | GRUENENTHAL GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-4439433-A | CEPHALOSPORIN ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1984-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | TRPV1, TRPV5, TRPV2 | MAPT 4129/4885CYP1A2 1857/4885CYP3A4 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.