Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062715 | 0.88 | NPC1 (0.46) | ALOX5SMN1; SMN2CYP3A4NPC1TSHR | |
| SCHEMBL16956761 | 0.85 | ALOX5 (0.46) | ALOX5SMN1; SMN2CYP3A4NPC1ABCG2 | |
| SCHEMBL16954520 | 0.83 | ALOX5 (0.49) | ALOX5SMN1; SMN2CYP3A4NPC1ABCG2 | |
| SCHEMBL9999712 | 0.82 | CYP3A4 (0.53) | ALOX5SMN1; SMN2CYP3A4NPC1TSHR | |
| SCHEMBL11067722 | 0.82 | CYP3A4 (0.59) | ALOX5SMN1; SMN2CYP3A4NPC1TSHR | |
| SCHEMBL9886148 | 0.80 | CYP19A1 (0.50) | ALOX5SMN1; SMN2CYP3A4TSHRALDH1A1 | |
| SCHEMBL6771209 | 0.79 | TSHR (0.59) | ALOX5SMN1; SMN2CYP3A4NPC1TSHR | |
| SCHEMBL16950489 | 0.79 | ALOX5 (0.45) | ALOX5SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL16958225 | 0.78 | ALOX5 (0.45) | ALOX5SMN1; SMN2CYP3A4NPC1ABCG2 | |
| SCHEMBL6582839 | 0.78 | CYP3A4 (0.46) | ALOX5SMN1; SMN2CYP3A4NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |