Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754499 | 0.75 | KMT2A (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10640876 | 0.72 | OPRM1 (0.49) | CYP1A2SLC6A3 | |
| SCHEMBL1152677 | 0.70 | OPRM1 (0.49) | SLC6A4 | |
| SCHEMBL11072043 | 0.70 | CYP1A2 (0.40) | CYP1A2SLC6A4 | |
| SCHEMBL5754493 | 0.69 | CHRM1 (0.37) | — | |
| SCHEMBL10637592 | 0.68 | OPRM1 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10637222 | 0.68 | OPRM1 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11075430 | 0.68 | OPRD1 (0.44) | SLC6A4 | |
| SCHEMBL10637823 | 0.67 | CYP3A4 (0.35) | SLC6A4 | |
| SCHEMBL10641018 | 0.66 | POLB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485109-A | 4-Aryl-4-piperidinecarbinols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| EP-0094018-A2 | 4-Aryl-4-piperidinecarbinols | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-11-16 | — | — | EP | disclosed |