Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10638230 | 0.80 | SIGMAR1 (0.43) | OPRM1OPRD1OPRK1OPRL1SIGMAR1 | |
| SCHEMBL1152677 | 0.78 | OPRM1 (0.49) | OPRM1OPRD1OPRK1SETD7P2RX7 | |
| SCHEMBL17888234 | 0.76 | OPRM1 (0.62) | CYP1A2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL11075045 | 0.74 | MEN1 (0.40) | CYP1A2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL10640876 | 0.73 | OPRM1 (0.49) | CYP1A2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL10641018 | 0.73 | POLB (0.42) | OPRM1MAPK1SMN1; SMN2 | |
| SCHEMBL11075430 | 0.72 | OPRD1 (0.44) | OPRM1OPRD1OPRK1OPRL1P2RX7 | |
| SCHEMBL10637780 | 0.72 | GRIN1 (0.41) | OPRM1OPRD1OPRK1OPRL1HTR2B | |
| SCHEMBL10637823 | 0.71 | CYP3A4 (0.35) | OPRM1OPRD1OPRK1SETD7SLC22A1 | |
| SCHEMBL6924321 | 0.70 | P2RX7 (0.44) | CYP1A2OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485109-A | 4-Aryl-4-piperidinecarbinols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| EP-0094018-A2 | 4-Aryl-4-piperidinecarbinols | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-11-16 | — | — | EP | disclosed |