SCHEMBL11066697

SCHEMBL11066697

OC(C1=CC=CC1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 6/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 3/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2C P18825 1/20 0.36
HIF1A Q16665 1/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17236552 0.81 ACACB (0.33)
SCHEMBL20792846 0.81 SMN1; SMN2 (0.35) MEN1MAPTCYP2C9KMT2ALMNA
SCHEMBL28838088 0.79 SLC6A3 (0.37) MEN1MAPTKMT2ALMNAKDM4E
SCHEMBL7719567 0.79 SLC6A3 (0.37) MEN1MAPTKMT2ALMNAKDM4E
SCHEMBL17236570 0.78 ALDH1A1 (0.45) MEN1MAPTKMT2ALMNAKDM4E
SCHEMBL9302592 0.78 TYR (0.39) MEN1KMT2ALMNAKDM4EADRA2A
SCHEMBL12846240 0.76 DPP4 (0.39) LMNAKDM4EADRA2AADRA2CHIF1A
Hydrochloric Acid SCHEMBL8677325 0.76 SLC6A2 (0.39) MEN1MAPTKMT2ALMNAKDM4E
Hydrochloric Acid SCHEMBL8677321 0.76 SLC6A2 (0.34) MEN1MAPTCYP2C9KMT2ALMNA
SCHEMBL29184525 0.75 LMNA (0.40) KMT2ALMNAKDM4EHIF1AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4484010-A POLYMER ANTIOXIDANT THE B. F. GOODRICH COMPANY (US) 1984-11-20 US disclosed
US-4484010-A POLYMER ANTIOXIDANT THE B. F. GOODRICH COMPANY (US) 1984-11-20 US disclosed
US-4484010-A POLYMER ANTIOXIDANT THE B. F. GOODRICH COMPANY (US) 1984-11-20 US disclosed
EP-0113666-A1 Hydroxybenzylcyclopentadienes and derivatives thereof The B.F. GOODRICH Company (US) 1984-07-18 EP disclosed
EP-0113666-A1 Hydroxybenzylcyclopentadienes and derivatives thereof The B.F. GOODRICH Company (US) 1984-07-18 EP disclosed
EP-0113666-A1 Hydroxybenzylcyclopentadienes and derivatives thereof The B.F. GOODRICH Company (US) 1984-07-18 EP disclosed