Pyridine

Pyridine

SCHEMBL11066795

N#Cc1cccc2c1Cc1ccccc1-2.c1ccncc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.46
PNMT P11086 1/20 0.41
CDK1 P06493 1/20 0.38
CDK2 P24941 1/20 0.38
SQOR Q9Y6N5 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36
DRD3 P35462 1/20 0.36
KCNH2 Q12809 1/20 0.36
NISCH Q9Y2I1 1/20 0.35
CYP17A1 P05093 1/20 0.35
MAOA P21397 1/20 0.35
HTT P42858 1/20 0.35
KDR P35968 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
HTR7 P34969 1/20 0.35
HTR2B P41595 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1033059 0.88 TRPA1 (0.50) TRPA1PNMTSQORNPC1RAB9A
SCHEMBL30940563 0.88 TRPA1 (0.50) TRPA1PNMTSQORNPC1RAB9A
SCHEMBL28405842 0.80 PNMT (0.49) TRPA1PNMTSQORNPC1RAB9A
Fluorene SCHEMBL29055454 0.79 MAOA (0.48) TRPA1PNMTNPC1RAB9ADRD3
Fluorene SCHEMBL23387530 0.79 MAOA (0.52) CDK1CDK2NPC1RAB9ACYP17A1
Fluorene SCHEMBL27936333 0.79 MAOA (0.52) CDK1CDK2NPC1RAB9ACYP17A1
Fluorene SCHEMBL25309211 0.79 MAOA (0.52) CDK1CDK2NPC1RAB9ACYP17A1
Fluorene SCHEMBL27983386 0.77 MAOA (0.50) CDK1CDK2NPC1RAB9ACYP17A1
Fluorene SCHEMBL28016247 0.77 MAOA (0.50) CDK1CDK2NPC1RAB9ACYP17A1
Fluorene SCHEMBL27945576 0.77 MAOA (0.50) CDK1CDK2NPC1RAB9ACYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0113293-A1 Liquid crystals family with a smectic A phase, and process for its preparation THOMSON-CSF (FR) 1984-07-11 EP disclosed