Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.54 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072744 | 0.85 | ADORA2B (0.51) | ADORA2BADORA1ADORA2A | |
| SCHEMBL11072524 | 0.84 | SIRT1 (0.55) | SIRT1SIRT3SIRT5SIRT2ADORA2B | |
| SCHEMBL11069848 | 0.83 | SIRT1 (0.51) | SIRT1SIRT3SIRT5SIRT2ADORA2B | |
| SCHEMBL3179805 | 0.83 | SIRT1 (0.54) | SIRT1SIRT3SIRT5SIRT2ADORA2B | |
| SCHEMBL9430500 | 0.82 | ADORA2A (0.60) | SIRT1SIRT3SIRT5ADORA2BADORA1 | |
| SCHEMBL7201941 | 0.82 | SIRT1 (0.62) | SIRT1SIRT3SIRT5SIRT2ADORA2B | |
| SCHEMBL7424268 | 0.81 | SIRT1 (0.50) | SIRT1SIRT3SIRT5SIRT2ADORA2B | |
| SCHEMBL11066305 | 0.80 | SIRT1 (0.54) | SIRT1SIRT3SIRT5SIRT2ADORA2B | |
| SCHEMBL11389501 | 0.79 | ADORA1 (0.61) | ADORA2BADORA1ADORA2A | |
| SCHEMBL4626790 | 0.78 | ADORA2A (0.58) | ADORA2BADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469698-A | SEDATIVES, TRANQUILIZERS | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1984-09-04 | — | — | US | claimed |