Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MDH2 | P40926 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30960130 | 0.91 | HTR2A (0.52) | HTR2APARP1SRD5A2EDNRAHTT | |
| SCHEMBL7390324 | 0.89 | HTR2A (0.55) | HTR2ASRD5A2EDNRAALDH1A1HPGD | |
| SCHEMBL8615935 | 0.86 | HTR2A (0.52) | HTR2ASRD5A2EDNRAALDH1A1HPGD | |
| SCHEMBL29138513 | 0.85 | HTR2A (0.52) | HTR2ASRD5A2EDNRAALDH1A1HPGD | |
| SCHEMBL23805228 | 0.84 | HTR2A (0.51) | HTR2ASRD5A2EDNRASGMS2 | |
| SCHEMBL12558840 | 0.84 | HTR2A (0.57) | HTR2ASRD5A2EDNRAHTTALDH1A1 | |
| SCHEMBL27528777 | 0.84 | NR4A2 (0.54) | HTR2ASRD5A2EDNRAHTTALDH1A1 | |
| SCHEMBL9023334 | 0.83 | GABRA1 (0.54) | HTR2AEDNRAHTT | |
| SCHEMBL23805270 | 0.82 | HTR2A (0.52) | HTR2ASRD5A2EDNRAALDH1A1HPGD | |
| SCHEMBL31089857 | 0.82 | HTR2A (0.60) | HTR2ASRD5A2EDNRAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045910-B1 | INDOLE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | Roche Diagnostics GmbH (DE) | 1984-10-10 | — | — | EP | disclosed |
| US-4442295-A | 3-Cyano indoles as intermediates for cardioselective compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-10 | — | — | US | disclosed |
| EP-0045910-A1 | Indole derivatives and process for their production | Roche Diagnostics GmbH (DE) | 1982-02-17 | — | — | EP | disclosed |