Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MDH2 | P40926 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390324 | 0.88 | HTR2A (0.55) | HTR2ASRD5A2ALDH1A1HPGDMDH2 | |
| SCHEMBL11067101 | 0.86 | HTR2A (0.53) | HTR2ASRD5A2ALDH1A1HPGDMDH2 | |
| SCHEMBL30960130 | 0.85 | HTR2A (0.52) | HTR2ASRD5A2ALDH1A1HPGDMDH2 | |
| SCHEMBL27528777 | 0.82 | NR4A2 (0.54) | HTR2ASRD5A2ALDH1A1HPGDMDH2 | |
| SCHEMBL9023334 | 0.81 | GABRA1 (0.54) | HTR2AEDNRAPTGER1 | |
| SCHEMBL29138513 | 0.81 | HTR2A (0.52) | HTR2ASRD5A2ALDH1A1HPGDMDH2 | |
| SCHEMBL23805228 | 0.81 | HTR2A (0.51) | HTR2ASRD5A2EDNRASGMS2 | |
| SCHEMBL12558840 | 0.81 | HTR2A (0.57) | HTR2ASRD5A2ALDH1A1HPGDMDH2 | |
| SCHEMBL2077171 | 0.81 | HTR2A (0.51) | HTR2ASRD5A2ALDH1A1HPGDMDH2 | |
| SCHEMBL28374945 | 0.79 | HTR2A (0.63) | HTR2ASRD5A2EDNRAMAOBSGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686154-B1 | NOVEL USE AS ANTI-INFLAMMATORY AGENTS FOR BIS-HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | HARBOR BRANCH OCEANOGRAPHIC (US) | 1998-04-22 | — | — | EP | disclosed |