Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.48 |
| ▸ | CHRNG | P07510 | 3/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.48 |
| ▸ | CHRND | Q07001 | 3/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067208 | 1.00 | ITGB3 (0.50) | ITGB3ITGA2BCHRNA1CHRNGCHRNB1 | |
| SCHEMBL29679713 | 0.87 | MMP2 (0.63) | ITGB3ITGA2BCHRNA1CHRNGCHRNB1 | |
| SCHEMBL30786037 | 0.87 | MMP2 (0.63) | ITGB3ITGA2BCHRNA1CHRNGCHRNB1 | |
| SCHEMBL30717893 | 0.84 | GNPAT (0.56) | ITGB3ITGA2BMMP2ERAP2LNPEP | |
| SCHEMBL29569077 | 0.84 | GNPAT (0.62) | ITGB3ITGA2BCHRNA1CHRNGCHRNB1 | |
| SCHEMBL14004105 | 0.83 | CHRNA1 (0.53) | ITGB3ITGA2BCHRNA1CHRNGCHRNB1 | |
| SCHEMBL29569357 | 0.82 | ERAP2 (0.61) | MMP2ERAP2LNPEP | |
| SCHEMBL11204317 | 0.81 | CPB2 (0.41) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL29540107 | 0.81 | ERAP2 (0.55) | CHRNA1CHRNGCHRNB1CHRNDERAP2 | |
| SCHEMBL24158507 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BCHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459225-A | ANALGESICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | disclosed |
| EP-0024664-B1 | PEPTIDE AMIDES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | disclosed |
| EP-0024664-A1 | Peptide amides and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-03-11 | — | — | EP | disclosed |