Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ATP4A | P20648 | 1/20 | 0.49 |
| ▸ | ATP4B | P51164 | 1/20 | 0.49 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16491623 | 0.83 | HTT (0.59) | MAPTMAPK1TDP1L3MBTL1ATP4A | |
| SCHEMBL8283853 | 0.81 | TSHR (0.50) | LTA4HMAPK14MAPTMAPK1TDP1 | |
| SCHEMBL3943486 | 0.80 | L3MBTL1 (0.51) | MAPTMAPK1TDP1L3MBTL1STAT3 | |
| SCHEMBL16415760 | 0.80 | MEN1 (0.52) | MAPTMAPK1TDP1L3MBTL1STAT3 | |
| SCHEMBL2675108 | 0.80 | LTA4H (0.58) | LTA4HMAPK14MAPTMAPK1TDP1 | |
| SCHEMBL3869852 | 0.78 | L3MBTL1 (0.49) | MAPTMAPK1TDP1L3MBTL1TSHR | |
| SCHEMBL12226851 | 0.78 | L3MBTL1 (0.49) | MAPTMAPK1TDP1L3MBTL1TSHR | |
| SCHEMBL4502335 | 0.78 | MAPT (0.49) | MAPTMAPK1TDP1L3MBTL1TSHR | |
| SCHEMBL6480247 | 0.78 | GRM5 (0.54) | MAPTMAPK1TDP1L3MBTL1STAT3 | |
| SCHEMBL8561627 | 0.76 | BDKRB2 (0.52) | DCPSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450164-A | ANTIULCER AND ANTISECRETORY AGENTS | SCHERING CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |