Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067472 | 0.90 | KCNH2 (0.54) | DRD4KCNH2SLC18A3 | |
| SCHEMBL11067861 | 0.87 | DRD4 (0.62) | DRD4DRD2CHRM2CHRM4CHRM5 | |
| SCHEMBL11066898 | 0.84 | DRD2 (0.53) | DRD4DRD2CHRM2CHRM4CHRM5 | |
| SCHEMBL11066967 | 0.81 | SCN1A (0.55) | DRD4TSHRL3MBTL1KCNH2SLC18A3 | |
| SCHEMBL11067922 | 0.78 | KCNH2 (0.49) | KCNH2SLC18A3 | |
| SCHEMBL11073897 | 0.77 | ABCB1 (0.62) | DRD4DRD2 | |
| SCHEMBL11061136 | 0.76 | KCNH2 (0.56) | DRD4DRD2KCNH2 | |
| SCHEMBL11067546 | 0.75 | KCNH2 (0.52) | DRD4DRD2CHRM2CHRM4CHRM5 | |
| Oxalic Acid SCHEMBL11060455 | 0.75 | ABCB1 (0.61) | DRD4DRD2 | |
| SCHEMBL11064919 | 0.75 | ADRB2 (0.51) | DRD4KCNH2SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |