Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | UNG | P13051 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728274 | 0.82 | CA12 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL26308648 | 0.78 | MAOB (0.47) | HTR7ALDH1A1UNGMAOAMAOB | |
| SCHEMBL5538035 | 0.78 | HTR7 (0.45) | HTR7ALDH1A1UNGMAOAMAOB | |
| SCHEMBL31023263 | 0.78 | HTR7 (0.45) | HTR7ALDH1A1UNGMAOAMAOB | |
| SCHEMBL11061209 | 0.78 | HTR7 (0.49) | HTR7ALDH1A1UNGMAOAMAOB | |
| SCHEMBL7199847 | 0.77 | CA12 (0.56) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL23109840 | 0.76 | FFAR1 (0.42) | HTR7ALDH1A1KMT2AMAPT | |
| SCHEMBL5540240 | 0.75 | HTR7 (0.49) | HTR7ALDH1A1UNGMAOAMAOB | |
| SCHEMBL2278503 | 0.75 | HTR7 (0.46) | HTR7ALDH1A1MAPTHTT | |
| SCHEMBL1220014 | 0.74 | CYP3A4 (0.47) | HTR7CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |