Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99646 | 0.84 | CA12 (0.65) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6003024 | 0.83 | CA12 (0.55) | CA12CA1CA2CA9ALDH1A1 | |
| Ethylene Glycol SCHEMBL10456795 | 0.78 | CA12 (0.38) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL2297932 | 0.78 | CA12 (0.55) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL14423965 | 0.78 | CYP2A6 (0.44) | ALDH1A1ALDH1A3ALDH3A1CYP2A6HSD17B10 | |
| SCHEMBL1585896 | 0.78 | CA12 (0.59) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL11067660 | 0.77 | HTR7 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL5498510 | 0.76 | ALDH1A1 (0.38) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10987838 | 0.76 | KDM4E (0.41) | CA12CA1CA2CA9ALDH1A1 | |
| Water SCHEMBL11215220 | 0.76 | CA12 (0.57) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475221-B1 | Syndiotactic 1,2-polybutadiene synthesis in an aqueous medium | GOODYEAR TIRE & RUBBER (US) | 1995-05-24 | — | — | EP | claimed |
| EP-0475221-A1 | Syndiotactic 1,2-polybutadiene synthesis in an aqueous medium | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-03-18 | — | — | EP | claimed |
| US-5011896-A | Polymerizing 1,3-butadiene in the presence of a cobalt-aluminum-conjugated diene catalyst, carbon disulfide, and benzaldehyde modifier | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-04-30 | — | — | US | claimed |
| US-4281019-A | 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1981-07-28 | — | — | US | claimed |
| JP-4234402-A | — | — | None | — | — | JP | disclosed |
| EP-0879834-B1 | Means to control particle size and eliminate fouling in the synthesis of syndiotactic 1,2-polybutadiene | GOODYEAR TIRE & RUBBER (US) | 2003-02-05 | — | — | EP | disclosed |
| US-6284844-B1 | CERTAIN SUBSTITUTED BENZOIC ACIDS CAN BE EMPLOYED TO DEACTIVATE TRANSITION METAL BASED CATALYST SYSTEMS. | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-09-04 | — | — | US | disclosed |
| US-6013720-A | AQUEOUS SLURRIES FOR COATING THE SURFACE OF RUBBER SLABS AND RUBBER PELLETS TO REDUCE THEIR STICKING TENDENCY, COMPRISED OF SYNDIOTACTIC-1,2-POLYBUTADIENE, AND ALSO INCLUDE A SUSPENDING AGENT AND WETTING AGENT | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| US-5986026-A | CATALYTIC POLYMERIZATION OF BUTADIENE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0893222-A2 | Partitioning agent for rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0879834-A1 | Means to control practicle size and eliminate fouling in the synthesis of syndiotactic 1,2-polybutadiene | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-11-25 | — | — | EP | disclosed |
| EP-0877035-A1 | Syndiotactic 1,2-polybutadiene synthesis | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-11-11 | — | — | EP | disclosed |
| US-5011896-A | Polymerizing 1,3-butadiene in the presence of a cobalt-aluminum-conjugated diene catalyst, carbon disulfide, and benzaldehyde modifier | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-5011896-A | Polymerizing 1,3-butadiene in the presence of a cobalt-aluminum-conjugated diene catalyst, carbon disulfide, and benzaldehyde modifier | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4977272-A | Radiation absorbers | THE STANDARD OIL COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4281019-A | 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4272546-A | ANTILIPEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1981-06-09 | — | — | US | disclosed |
| US-4198522-A | HYPOLIPIDEMIC ACND ANTI-ATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-04-15 | — | — | US | disclosed |
| US-4196208-A | ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |