Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | UNG | P13051 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5538035 | 1.00 | HTR7 (0.45) | HTR7ALDH1A1UNGDRD2DRD1 | |
| SCHEMBL5540240 | 0.85 | HTR7 (0.49) | HTR7ALDH1A1UNGDRD2DRD1 | |
| SCHEMBL5915750 | 0.82 | HTR7 (0.53) | HTR7ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL6187008 | 0.81 | DRD1 (0.44) | ALDH1A1DRD1MAPTLMNAALDH1A3 | |
| SCHEMBL9101071 | 0.81 | HTR7 (0.52) | HTR7ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL7024378 | 0.81 | TP53 (0.48) | HTR7ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL7285414 | 0.80 | HTR7 (0.51) | HTR7ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL3363357 | 0.79 | MAPT (0.50) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11067660 | 0.78 | HTR7 (0.43) | HTR7ALDH1A1UNGMAPTHTT | |
| SCHEMBL95532 | 0.78 | ALDH1A1 (0.48) | HTR7ALDH1A1UNGMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299400-A1 | Transcription Factor GLI1 Inhibitors and Uses Thereof | UNIVERSITY OF CONNECTICUT (US) | 2024-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299400-A1 | Transcription Factor GLI1 Inhibitors and Uses Thereof | GLI1, GLI2, SHH | HTR7 4045/4885ALDH1A1 550/4885UNG 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.