Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.53 |
| ▸ | DRD4 | P21917 | 6/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063923 | 0.87 | KMT2A (0.61) | KMT2AMEN1ATMALDH1A1LMNA | |
| SCHEMBL11066890 | 0.85 | ABCB1 (0.57) | KMT2AMEN1ATMALDH1A1LMNA | |
| Oxalic Acid SCHEMBL11064628 | 0.82 | ABCB1 (0.57) | KMT2AMEN1ATMALDH1A1LMNA | |
| SCHEMBL10580555 | 0.78 | MAPT (0.57) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL11066226 | 0.77 | DRD4 (0.62) | KMT2AMEN1ATMDRD4GAA | |
| SCHEMBL11065039 | 0.76 | DRD4 (0.60) | KMT2AMEN1ATMABCB1DRD4 | |
| SCHEMBL9750911 | 0.75 | KMT2A (0.81) | KMT2AMEN1ATMALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9751034 | 0.75 | KMT2A (0.80) | KMT2AMEN1ATMALDH1A1LMNA | |
| SCHEMBL11072463 | 0.74 | DRD2 (0.46) | LMNADRD4ADRB2ADRB1ADRB3 | |
| SCHEMBL11066891 | 0.74 | ABCB1 (0.61) | KMT2AMEN1ATMABCB1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |