Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 17/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 17/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065562 | 0.85 | PDE3B (0.45) | PDE3BPDE3AS1PR5P2RY12 | |
| SCHEMBL11062867 | 0.85 | HTR6 (0.44) | PDE3BPDE3A | |
| SCHEMBL11065742 | 0.80 | PDE3B (0.55) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL11062167 | 0.80 | PDE3B (0.57) | PDE3BPDE3A | |
| SCHEMBL11071217 | 0.80 | PDE3B (0.48) | PDE3BPDE3AP2RY12 | |
| SCHEMBL11067928 | 0.80 | PDE3B (0.48) | PDE3BPDE3AP2RY12 | |
| SCHEMBL11058328 | 0.74 | PDE3B (0.49) | PDE3BPDE3AP2RY12 | |
| SCHEMBL11068086 | 0.74 | PDE3B (0.42) | PDE3BPDE3A | |
| SCHEMBL11069955 | 0.74 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL11067436 | 0.73 | PDE3B (0.47) | PDE3BPDE3AP2RY12PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |