Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30162670 | 0.87 | ALOX5 (0.60) | ALOX5ELANEPTGS1PTGDRPTGDR2 | |
| SCHEMBL22071934 | 0.87 | ALOX5 (0.60) | ALOX5ELANEPTGS1PTGDRPTGDR2 | |
| SCHEMBL27458540 | 0.87 | L3MBTL1 (0.56) | L3MBTL1MAPK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL985212 | 0.85 | L3MBTL1 (0.54) | L3MBTL1MAPK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27695947 | 0.84 | LMNA (0.39) | L3MBTL1MAPK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10872957 | 0.84 | ALOX5 (0.54) | L3MBTL1MAPK1ALDH1A1ALOX5ELANE | |
| SCHEMBL27695932 | 0.82 | LMNA (0.37) | L3MBTL1MAPK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24158070 | 0.82 | ALOX5 (0.61) | L3MBTL1ALOX5PTGS1MEN1KMT2A | |
| SCHEMBL9186206 | 0.82 | ELANE (0.47) | L3MBTL1MAPK1ALDH1A1LMNAALOX5 | |
| SCHEMBL15500145 | 0.80 | ELANE (0.44) | L3MBTL1MAPK1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468524-A | Alkenylphenyl substituted acrylates or methacrylates | CIBA-GEIGY CORPORATION (US) | 1984-08-28 | — | — | US | disclosed |
| US-4387204-A | Self-crosslinkable monomer composition containing alkenylphenyl substituted acrylates or methacrylates | CIBA-GEIGY CORPORATION (US) | 1983-06-07 | — | — | US | disclosed |
| EP-0038300-A1 | Polymerisable composition and (meth)acrylic ester | CIBA-GEIGY AG (CH) | 1981-10-21 | — | — | EP | disclosed |