Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | ESR1 | P03372 | 12/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17633012 | 0.84 | SMN1; SMN2 (0.49) | PPARAPPARGKMT2AGAASMN1; SMN2 | |
| SCHEMBL6664136 | 0.84 | SMN1; SMN2 (0.49) | PPARAPPARGKMT2AGAASMN1; SMN2 | |
| SCHEMBL8935882 | 0.83 | PPARG (0.67) | PPARAPPARGMEN1KMT2AGAA | |
| SCHEMBL8821208 | 0.83 | PPARG (0.67) | PPARAPPARGMEN1KMT2AGAA | |
| SCHEMBL10741839 | 0.81 | THRB (0.49) | PPARAPPARGSMN1; SMN2LTB4R | |
| SCHEMBL9315719 | 0.80 | KMT2A (0.56) | PPARAPPARGESR1ESR2MEN1 | |
| SCHEMBL9659165 | 0.79 | PPARG (0.56) | PPARAPPARGESR1ESR2MEN1 | |
| SCHEMBL8586491 | 0.79 | LTB4R (0.58) | PPARAPPARGSMN1; SMN2LTB4R | |
| SCHEMBL3144299 | 0.78 | PPARA (0.50) | PPARAPPARGSMN1; SMN2LTB4R | |
| SCHEMBL17014662 | 0.78 | SLC6A2 (0.45) | ESR1ESR2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424231-A | Compounds | FISONS LIMITED (GB) | 1984-01-03 | — | — | US | disclosed |