Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.67 |
| ▸ | MAOB | P27338 | 6/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067221 | 0.84 | MAOB (0.79) | MAOAMAOBTMEM97SIGMAR1DRD4 | |
| SCHEMBL11070336 | 0.84 | MAOA (0.93) | MAOAMAOBSLC6A4DRD2SLC6A2 | |
| SCHEMBL10570662 | 0.83 | DRD2 (0.66) | MAOAMAOBDRD4SLC6A4DRD2 | |
| SCHEMBL11065044 | 0.81 | MAOA (0.61) | MAOAMAOBTMEM97SIGMAR1DRD4 | |
| SCHEMBL11071104 | 0.81 | MAOA (0.61) | MAOAMAOBTMEM97SIGMAR1DRD4 | |
| Oxalic Acid SCHEMBL11062992 | 0.81 | MAOA (0.86) | MAOAMAOBDRD4DRD2 | |
| SCHEMBL11066390 | 0.80 | MAOA (1.00) | MAOAMAOBDRD2 | |
| SCHEMBL11062856 | 0.80 | MAOA (1.00) | MAOAMAOBDRD2 | |
| Hydrochloric Acid SCHEMBL11067443 | 0.80 | MAOA (0.60) | MAOAMAOBTMEM97SIGMAR1DRD4 | |
| SCHEMBL11066624 | 0.79 | MAOB (0.87) | MAOAMAOBTMEM97SIGMAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |