Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11067443 | 0.99 | MAOA (0.60) | MAOAMAOBDRD4MEN1KMT2A | |
| SCHEMBL11065083 | 0.97 | MAOA (0.65) | MAOAMAOBDRD4MEN1KMT2A | |
| SCHEMBL11073307 | 0.95 | MAOA (0.57) | MAOAMAOBDRD4MEN1KMT2A | |
| SCHEMBL11063504 | 0.90 | KCNH2 (0.50) | MAOAMAOBDRD4MEN1KMT2A | |
| SCHEMBL11070939 | 0.89 | MAOA (0.52) | MAOAMAOBDRD4MEN1KMT2A | |
| SCHEMBL11073435 | 0.86 | HTR7 (0.48) | MAOAMAOBDRD4MEN1KMT2A | |
| SCHEMBL10576436 | 0.85 | MAOA (0.63) | MAOAMAOBDRD4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11070539 | 0.85 | HTR7 (0.47) | MAOAMAOBDRD4SIGMAR1HRH3 | |
| SCHEMBL11071104 | 0.84 | MAOA (0.61) | MAOAMAOBDRD4MEN1KMT2A | |
| SCHEMBL11073566 | 0.83 | MAOA (0.54) | MAOAMAOBDRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |