Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1974134 | 0.85 | GRM2 (0.53) | MAPTLMNAL3MBTL1KMT2AGRM2 | |
| SCHEMBL9063261 | 0.84 | LMNA (0.63) | MAPTLMNAL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL9857703 | 0.84 | LMNA (0.63) | MAPTLMNAL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL11065098 | 0.82 | LMNA (0.56) | LMNAL3MBTL1KMT2AGRM2HTT | |
| SCHEMBL18562432 | 0.76 | L3MBTL1 (0.59) | MAPTLMNAL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL5735824 | 0.76 | MKNK1 (0.59) | MAPTL3MBTL1CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL15447704 | 0.75 | MAPT (0.52) | MAPTLMNAL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL19479573 | 0.75 | MAPT (0.52) | MAPTLMNAL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL17901029 | 0.75 | LMNA (0.72) | MAPTLMNAL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL2805987 | 0.75 | LMNA (0.72) | MAPTLMNAL3MBTL1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427682-A | ANTICOAGULANTS, ANTIINFLAMMATORY, HYPOTENSIVE, OR ANTIALLERGEN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |