Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641242 | 0.93 | LMNA (0.47) | LMNAMAPTALDH1A1GAAPKM | |
| SCHEMBL605142 | 0.87 | LMNA (0.55) | LMNAMAPTALDH1A1GAACA1 | |
| SCHEMBL23887826 | 0.87 | LMNA (0.55) | LMNAMAPTALDH1A1GAACA1 | |
| SCHEMBL10700943 | 0.83 | NAAA (0.45) | LMNANAAAALDH1A1L3MBTL1HTT | |
| SCHEMBL28453248 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1GAACA1CA2 | |
| SCHEMBL28453243 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1GAACA1CA2 | |
| SCHEMBL10641244 | 0.79 | LMNA (0.47) | LMNAMAPTALDH1A1GAACA1 | |
| SCHEMBL2246161 | 0.79 | ALDH1A1 (0.49) | LMNAMAPTALDH1A1GAAPKM | |
| SCHEMBL29239458 | 0.78 | ALDH1A1 (0.44) | LMNAMAPTALDH1A1GAAPKM | |
| SCHEMBL25311278 | 0.78 | ALDH1A1 (0.48) | LMNAMAPTALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127048-A2 | Optically active diphenyl ether derivatives | BAYER AG (DE) | 1984-12-05 | — | — | EP | disclosed |