Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 18/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095289 | 0.88 | PRKCZ (0.52) | PRKCZPDE5AEGFRERBB2 | |
| SCHEMBL11060046 | 0.83 | PRKCZ (0.51) | PRKCZPDE5A | |
| SCHEMBL11060811 | 0.83 | PRKCZ (0.56) | PRKCZPDE5AEGFRERBB2 | |
| SCHEMBL11058379 | 0.81 | PRKCZ (0.57) | PRKCZPDE5A | |
| SCHEMBL11058366 | 0.80 | PRKCZ (0.48) | PRKCZPDE5AEGFRERBB2 | |
| SCHEMBL908137 | 0.80 | PRKCZ (0.58) | PRKCZPDE5AEGFR | |
| SCHEMBL11094507 | 0.80 | PRKCZ (0.47) | PRKCZPDE5AEGFR | |
| SCHEMBL908494 | 0.77 | CA1 (0.56) | PRKCZPDE5AEGFRERBB2 | |
| SCHEMBL908259 | 0.77 | PRKCZ (0.41) | PRKCZEGFRERBB2 | |
| SCHEMBL11057378 | 0.77 | MEN1 (0.56) | PRKCZPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451479-A | ANTIINFLAMMATORY | AMERICAN CYANAMID COMPANY (US) | 1984-05-29 | — | — | US | disclosed |
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4348527-A | ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |