Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046668 | 0.89 | GABRA1 (0.46) | THRBTHRAALDH1A1GABRA1GABRB2 | |
| SCHEMBL11062459 | 0.80 | THRB (0.39) | THRBTHRAALDH1A1CYP3A4TSHR | |
| SCHEMBL11063477 | 0.78 | THRB (0.39) | THRBTHRAALDH1A1GABRA1GABRB2 | |
| SCHEMBL311912 | 0.77 | THRA (0.60) | THRBTHRAALDH1A1TSHRELANE | |
| SCHEMBL11062497 | 0.76 | ELANE (0.38) | THRBTHRAALDH1A1CYP3A4TSHR | |
| SCHEMBL11781028 | 0.74 | PTGS1 (0.52) | ALDH1A1TSHRPTGDRPTGDR2ALOX5 | |
| SCHEMBL311913 | 0.73 | THRB (0.64) | THRBALDH1A1CYP3A4TSHRGABRA1 | |
| SCHEMBL21620956 | 0.73 | KDM4E (0.47) | ALOX5PTGS1SRD5A1MAPTELANE | |
| SCHEMBL9771547 | 0.70 | KDM4E (0.48) | ALDH1A1CYP3A4GABRA1GABRB2ALOX5 | |
| SCHEMBL15302145 | 0.69 | TYMS (0.43) | THRBTHRAALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468524-A | Alkenylphenyl substituted acrylates or methacrylates | CIBA-GEIGY CORPORATION (US) | 1984-08-28 | — | — | US | disclosed |
| US-4387204-A | Self-crosslinkable monomer composition containing alkenylphenyl substituted acrylates or methacrylates | CIBA-GEIGY CORPORATION (US) | 1983-06-07 | — | — | US | disclosed |
| EP-0038300-A1 | Polymerisable composition and (meth)acrylic ester | CIBA-GEIGY AG (CH) | 1981-10-21 | — | — | EP | disclosed |