Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 8/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039281 | 0.88 | KDM4E (0.63) | LMNAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL11272206 | 0.86 | LMNA (0.48) | LMNAKDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL1038244 | 0.84 | KDM4E (0.61) | LMNAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL19242935 | 0.83 | KDM4E (0.66) | LMNAKDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL27546739 | 0.80 | LMNA (0.48) | LMNAKDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL11277251 | 0.79 | KDM4E (0.46) | LMNAKDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL2798566 | 0.78 | KDM4E (0.75) | LMNAKDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL7037717 | 0.78 | PDE3B (0.54) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL10285854 | 0.78 | KDM4E (0.65) | KDM4EALDH1A1TSHRHPGDGAA | |
| SCHEMBL11272074 | 0.78 | PDE3B (0.54) | LMNAKDM4EPDE3BPDE3ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |