Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068260 | 0.93 | ADAMTS4 (0.37) | ADAMTS4TRPV3P2RX3L3MBTL1TDP1 | |
| SCHEMBL11068255 | 0.93 | ADAMTS4 (0.37) | ADAMTS4TRPV3P2RX3L3MBTL1TDP1 | |
| SCHEMBL11072044 | 0.85 | ADAMTS4 (0.36) | ADAMTS4TRPV3P2RX3L3MBTL1TDP1 | |
| SCHEMBL11284538 | 0.83 | P2RX3 (0.35) | ADAMTS4TRPV3P2RX3L3MBTL1TDP1 | |
| SCHEMBL11070976 | 0.82 | TRPV3 (0.38) | ADAMTS4TRPV3P2RX3L3MBTL1TDP1 | |
| SCHEMBL11072017 | 0.82 | ADAMTS4 (0.38) | ADAMTS4TRPV3P2RX3L3MBTL1TDP1 | |
| SCHEMBL11065707 | 0.82 | ADAMTS4 (0.39) | ADAMTS4TRPV3P2RX3L3MBTL1TDP1 | |
| SCHEMBL11478773 | 0.81 | ADAMTS4 (0.39) | ADAMTS4TRPV3P2RX3L3MBTL1TDP1 | |
| SCHEMBL11069125 | 0.79 | ADAMTS4 (0.38) | ADAMTS4TRPV3P2RX3L3MBTL1TDP1 | |
| SCHEMBL11279541 | 0.78 | P2RX3 (0.34) | ADAMTS4TRPV3P2RX3L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447613-A | Pyridyl esters and thiolesters of aminoalkanoic acids | ZOECON CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4269981-A | Certain pyridylmethyl esters of formamido-lower-alkanoates and derivatives thereof | ZOECON CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |
| US-4247701-A | Certain pesticidal substituted amino lower-alkanoates or lower-alkano-thioates containing pyridyl in the ester portion | ZOECON CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |