Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072794 | 0.89 | KCNH2 (0.42) | MEN1KMT2ASIGMAR1HTR1AMCHR1 | |
| SCHEMBL11068654 | 0.84 | HTR1A (0.43) | MEN1KMT2AHTR1AMCHR1KCNH2 | |
| SCHEMBL11066882 | 0.84 | CYP2J2 (0.51) | KMT2ASIGMAR1HTR1AKCNH2 | |
| SCHEMBL11068619 | 0.75 | KDM4E (0.45) | HRH3KCNH2SOS1 | |
| Hydrochloric Acid SCHEMBL11067172 | 0.74 | SMN1; SMN2 (0.46) | MEN1KMT2AHRH3KCNH2SOS1 | |
| SCHEMBL11070666 | 0.74 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL11065672 | 0.74 | MEN1 (0.50) | MEN1KMT2AHTR1AMCHR1KCNH2 | |
| SCHEMBL11353192 | 0.73 | GRIN2B (0.46) | MEN1KMT2AHTR1AKCNH2 | |
| SCHEMBL11358395 | 0.72 | HTR2A (0.53) | SIGMAR1 | |
| SCHEMBL11359393 | 0.72 | CYP2J2 (0.50) | KMT2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |