Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065275 | 0.83 | ADORA2B (0.45) | ABL1 | |
| SCHEMBL11073568 | 0.77 | POLB (0.42) | ABL1 | |
| SCHEMBL11069334 | 0.74 | MTOR (0.55) | — | |
| SCHEMBL11066718 | 0.73 | ADORA2B (0.44) | ABL1 | |
| SCHEMBL7270939 | 0.73 | MTOR (0.45) | — | |
| SCHEMBL11069278 | 0.72 | ADORA2B (0.43) | ABL1 | |
| SCHEMBL11071690 | 0.72 | ADORA2B (0.42) | ABL1 | |
| SCHEMBL11070623 | 0.72 | ADORA2B (0.42) | ABL1 | |
| SCHEMBL7272778 | 0.71 | DYRK1A (0.45) | — | |
| SCHEMBL7968533 | 0.71 | PSEN1 (0.66) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448780-A | N-(Lower-alkyl)-N'-[5-(pyridinyl)-2-pyridinyl]ureas and cardiotonic use thereof | STERLING DRUG INC. (US) | 1984-05-15 | — | — | US | disclosed |