Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 4/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 7/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 7/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 7/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THPO | P40225 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653075 | 0.78 | GRIN2D (0.55) | KMOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8871995 | 0.76 | PSMB8 (0.58) | NOS1NOS3NOS2GRIN2DGRIN3B | |
| SCHEMBL15333188 | 0.73 | KIF11 (0.41) | NOS1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15329645 | 0.73 | KIF11 (0.41) | NOS1NOS3NOS2GRIN2DGRIN3B | |
| SCHEMBL6429912 | 0.73 | OGT (0.63) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11119376 | 0.71 | GRIN2D (0.41) | NOS1NOS3NOS2GRIN2DGRIN3B | |
| SCHEMBL9679621 | 0.64 | KMO (0.59) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL6407742 | 0.63 | GRIN2D (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3360077 | 0.63 | DAO (0.46) | LMNACYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL8873073 | 0.63 | GRIN2D (0.52) | KMONOS1NOS3NOS2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123151-A1 | Benzobisoxazinetetrones | RORER PHARMACEUTICAL CORPORATION (US) | 1984-10-31 | — | — | EP | disclosed |
| US-4476125-A | Benzobisoxazinetetrones and anti-allergic use thereof | USV PHARMACEUTICAL CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |