Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 11/20 | 0.46 |
| ▸ | DDO | Q99489 | 5/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5040720 | 0.71 | SMYD3 (0.40) | KDM4ELMNACYP1A2GAAMAPT | |
| SCHEMBL1244189 | 0.70 | SMYD3 (0.54) | DAOKDM4ELMNAMAPTALOX15 | |
| SCHEMBL3360401 | 0.70 | DAO (0.46) | DAODDOMEN1GLACYP3A4 | |
| SCHEMBL2406831 | 0.69 | SMYD3 (0.53) | DAOKDM4EPOLBMAPTL3MBTL1 | |
| SCHEMBL21691076 | 0.68 | CYP2A6 (0.40) | CYP1A2SMYD3 | |
| SCHEMBL3360781 | 0.68 | DAO (0.53) | DAODDO | |
| SCHEMBL1242690 | 0.67 | SMYD3 (0.53) | KDM4ELMNACYP1A2GAAMAPT | |
| SCHEMBL19265216 | 0.67 | SMYD3 (0.51) | DAOKDM4ELMNAPOLBGAA | |
| SCHEMBL1673129 | 0.67 | NOS1 (0.37) | PTGS1PTGS2KDM4ELMNATP53 | |
| SCHEMBL3435849 | 0.67 | DAO (0.45) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |