Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10803691 | 0.81 | TDP1 (0.43) | TDP1HSD17B10ALDH1A1HPGDALOX15 | |
| SCHEMBL11271074 | 0.81 | HPGD (0.48) | TDP1HSD17B10ALDH1A1HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL11264387 | 0.79 | HPGD (0.47) | TDP1HSD17B10ALDH1A1HPGDALOX15 | |
| SCHEMBL11061402 | 0.79 | ALDH1A1 (0.36) | TDP1HSD17B10ALDH1A1HPGDALOX15 | |
| SCHEMBL11064529 | 0.78 | ALDH1A1 (0.43) | TDP1HSD17B10ALDH1A1HPGDALOX15 | |
| SCHEMBL11073590 | 0.76 | ALDH1A1 (0.37) | TDP1HSD17B10ALDH1A1HPGDALOX15 | |
| SCHEMBL11070577 | 0.74 | GAA (0.41) | TDP1HSD17B10ALDH1A1HPGDALOX15 | |
| SCHEMBL11209782 | 0.73 | ALDH1A1 (0.44) | TDP1HSD17B10ALDH1A1HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL11212030 | 0.72 | ALDH1A1 (0.43) | TDP1HSD17B10ALDH1A1HPGDALOX15 | |
| SCHEMBL23544604 | 0.71 | HPGD (0.53) | TDP1HSD17B10ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |