Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11264387 | 0.98 | HPGD (0.47) | HPGDTSHRTDP1HSD17B10ALDH1A1 | |
| SCHEMBL11276126 | 0.89 | HSD17B3 (0.44) | HPGDTSHRTDP1HSD17B10ALDH1A1 | |
| SCHEMBL10803691 | 0.86 | TDP1 (0.43) | HPGDTSHRTDP1HSD17B10ALDH1A1 | |
| SCHEMBL3646867 | 0.83 | ALDH1A1 (0.44) | HPGDTSHRTDP1HSD17B10ALDH1A1 | |
| SCHEMBL11209782 | 0.83 | ALDH1A1 (0.44) | HPGDTSHRTDP1HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11276211 | 0.82 | ALDH1A1 (0.43) | HPGDTSHRTDP1HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11212030 | 0.82 | ALDH1A1 (0.43) | HPGDTSHRTDP1HSD17B10ALDH1A1 | |
| SCHEMBL23544604 | 0.82 | HPGD (0.53) | HPGDTSHRTDP1HSD17B10ALDH1A1 | |
| SCHEMBL11231775 | 0.81 | LMNA (0.42) | HPGDTSHRTDP1HSD17B10ALDH1A1 | |
| SCHEMBL11068908 | 0.81 | TDP1 (0.39) | HPGDTSHRTDP1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |