Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064529 | 0.91 | ALDH1A1 (0.43) | ALDH1A1TSHRRECQLHPGDALOX15 | |
| SCHEMBL11073590 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TSHRRECQLHPGDALOX15 | |
| SCHEMBL11070577 | 0.86 | GAA (0.41) | ALDH1A1TSHRRECQLHPGDALOX15 | |
| SCHEMBL11071632 | 0.82 | MAPT (0.42) | ALDH1A1TSHRRECQLHPGDALOX15 | |
| SCHEMBL11068685 | 0.81 | HSD17B3 (0.41) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11068908 | 0.79 | TDP1 (0.39) | ALDH1A1TSHRRECQLHPGDALOX15 | |
| SCHEMBL11279686 | 0.73 | HCAR3 (0.52) | ALDH1A1RECQLHPGDLMNAMAPT | |
| SCHEMBL11071289 | 0.69 | KDM4E (0.45) | ALDH1A1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL23544604 | 0.69 | HPGD (0.53) | ALDH1A1TSHRRECQLHPGDALOX15 | |
| SCHEMBL11068912 | 0.68 | METAP2 (0.45) | ALDH1A1TSHRHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |