Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072384 | 0.77 | MAPT (0.35) | MAPTSMN1; SMN2HPGDCNR2POLB | |
| SCHEMBL11069369 | 0.77 | CASP1 (0.39) | CNR2KDM4EKMT2ASLC5A1SLC5A2 | |
| SCHEMBL11265183 | 0.73 | EPHX2 (0.38) | SMN1; SMN2HPGDCNR2ACP3KDM4E | |
| SCHEMBL11387511 | 0.72 | HPGD (0.32) | SMN1; SMN2HPGDPOLBKMT2APPARG | |
| SCHEMBL11388184 | 0.68 | ALDH1A1 (0.41) | MAPTSMN1; SMN2POLBMAPK1KMT2A | |
| Acetic Acid SCHEMBL10562657 | 0.66 | ACP3 (0.47) | SMN1; SMN2HPGDCNR2POLBACP3 | |
| SCHEMBL7175765 | 0.66 | MAPT (0.40) | MAPTSMN1; SMN2POLBMAPK1KMT2A | |
| SCHEMBL29268488 | 0.66 | EPHX2 (0.46) | SMN1; SMN2CNR2POLBACP3MAPK1 | |
| Hydrochloric Acid SCHEMBL4512926 | 0.66 | CNR2 (0.44) | MAPTSMN1; SMN2HPGDCNR2POLB | |
| SCHEMBL1927969 | 0.65 | CNR2 (0.49) | CNR2POLBACP3MAPK1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435395-A | HYPOTENSIVE AGENTS | USV PHARMACEUTICAL CORPORATION (US) | 1984-03-06 | — | — | US | disclosed |