Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069369 | 0.86 | CASP1 (0.39) | EPHX2PPARGCNR2KDM4EKMT2A | |
| SCHEMBL11252362 | 0.81 | CASP1 (0.48) | EPHX2KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11265282 | 0.79 | ALDH1A1 (0.43) | KDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL11266327 | 0.77 | MMP8 (0.47) | KMT2AALDH1A1CYP1A2TDP1SLC6A2 | |
| SCHEMBL11255136 | 0.77 | ALDH1A1 (0.51) | KDM4EKMT2AALDH1A1CYP1A2TDP1 | |
| SCHEMBL29268488 | 0.76 | EPHX2 (0.46) | EPHX2PPARGCNR2KDM4EKMT2A | |
| SCHEMBL11072379 | 0.75 | EPHX2 (0.37) | EPHX2PPARGCNR2KDM4EKMT2A | |
| SCHEMBL6929206 | 0.74 | KDM4E (0.44) | EPHX2PPARGCNR2KDM4EKMT2A | |
| SCHEMBL29226191 | 0.74 | KMT2A (0.52) | EPHX2PPARGCNR2KDM4EKMT2A | |
| SCHEMBL11069375 | 0.73 | MAPT (0.39) | EPHX2PPARGCNR2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |