Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.75 |
| ▸ | ALB | P02768 | 2/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.75 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.75 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.75 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.75 |
| ▸ | DRD3 | P35462 | 1/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.75 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.72 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.72 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13217954 | 0.93 | GABRB2 (0.83) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL6642164 | 0.93 | GABRB2 (0.66) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL10526954 | 0.89 | TSPO (0.68) | TSPOALBOPRK1KCNH2NR1I2 | |
| Alpidem SCHEMBL4014704 | 0.87 | TSPO (0.83) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL13217931 | 0.86 | TSPO (0.60) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL3022501 | 0.86 | TSPO (0.60) | TSPOALBOPRK1KCNH2NR1I2 | |
| Alpidem SCHEMBL122619 | 0.86 | TSPO (1.00) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL23624275 | 0.85 | TSPO (0.69) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL8150 | 0.84 | GABRA2 (0.70) | TSPOALBOPRK1KCNH2NR1I2 | |
| Zolpidem SCHEMBL80516 | 0.84 | GABRB2 (1.00) | TSPOALBOPRK1KCNH2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460592-A | HYPNOTIC | SYNTHELABO | 1984-07-17 | — | — | US | disclosed |