Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956420 | 0.89 | MAPT (0.36) | APLNRHTTKMT2ATDP1GAA | |
| SCHEMBL11066089 | 0.80 | MAPT (0.36) | APLNRHTTLMNAGAASMN1; SMN2 | |
| SCHEMBL11062434 | 0.80 | MAPT (0.36) | APLNRHTTALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11055924 | 0.77 | MAPK1 (0.38) | MAP3K7TAB1HTTKMT2ANPC1 | |
| SCHEMBL11063670 | 0.75 | CDC7 (0.34) | MAP3K7TAB1KMT2ALMNANPC1 | |
| SCHEMBL11058623 | 0.73 | ATR (0.40) | MAP3K7TAB1HTTKMT2ATDP1 | |
| SCHEMBL10959912 | 0.72 | MAPT (0.36) | HTTKMT2ALMNAGAASMN1; SMN2 | |
| SCHEMBL11055958 | 0.71 | HTT (0.40) | HTTKMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL11061052 | 0.69 | MAPK1 (0.41) | MAP3K7TAB1HTTNPC1GAA | |
| SCHEMBL10957823 | 0.68 | ALDH1A1 (0.37) | HTTKMT2ATDP1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |