Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.67 |
| ▸ | MAPT | P10636 | 10/20 | 0.63 |
| ▸ | LMNA | P02545 | 8/20 | 0.63 |
| ▸ | HTT | P42858 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956783 | 0.94 | MEN1 (0.64) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL7033500 | 0.87 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL11972956 | 0.87 | MEN1 (0.60) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL6301912 | 0.87 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL14633632 | 0.87 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL4124277 | 0.86 | MEN1 (0.74) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL11047722 | 0.86 | MEN1 (0.74) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL12069189 | 0.86 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL29988517 | 0.86 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL9453953 | 0.83 | RAB9A (0.66) | ALDH1A1SMN1; SMN2MAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461821-A | Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound | FUJI PHOTO FILM CO., LTD. (JP) | 1984-07-24 | — | — | US | disclosed |